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хромозомске абнормалности
Проблеми са хромозомима (било наслеђени или проузроковани мутацијом), који доводе до Дауновог синдрома и других абнормалности. Поцењено је да је половина свих побачаја у првом тромесечју настала као последица хромозомских абнормалности.
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