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skrini mitatu
Mtihani damu aliyopewa mwanamke kati ya wiki 15 na 18 za mimba skrini kwa ongezeko la hatari ya mtoto kuwa na kasoro kuzaliwa. Viwango vya juu ya AFP inaweza kuhusishwa na kasoro neural tyubi; viwango vya chini inaweza kuhusishwa na Down syndrome. Mtihani ni kutumika kuamua kama zaidi ya kupima vamizi, kama vile amniocentesis, inahitajika.
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